Statistics and Data Science Seminar
Ying Zhou
UIC
D-OPTIMAL DESIGNS FOR COMPLEX NONLINEAR MODELS
Abstract: D-optimal designs for nonlinear chemical kinetics model and 2n-compartment
models are investigated. We develop a method to obtain lower bounds of the
maximal numbers of D-optimal design points to facility the computational
search for the optimal design points in practice. We also investigate the
conditions when the D-optimal design is the saturated design for bounded and
unbounded design spaces. For each model discussed, the D-efficiency when the
parameter misspecification happens is discussed.
Wednesday January 27, 2010 at 3:00 PM in SEO 636