Statistics and Data Science Seminar
Paul Livermore Auer
University of Wisconsin at Milwaukee
Statistical issues with drawing associations between rare genetic variants and common human diseases.
Abstract: To date, much of the work in understanding the genetic basis of common diseases has focused on genetic variants that exist with high frequency in human populations. Recently, the focus has shifted to investigating the role that rare genetic variants may play. Genetic studies of rare variants bring with them a host of statistical issues including decreased statistical power and missing data. We examine these issues and demonstrate the performance of solutions with both real and simulated data.
Wednesday April 9, 2014 at 4:00 PM in SEO 636