Statistics and Data Science Seminar
H.M. James Hung, PhD
Director, CDER, FDA
Adaptation of Clinical Trial Design
Abstract: A topic of great interest in the recent decade is design adaptation for clinical trials using the data accumulating during the course of the trial. There are good reasons for such modification of design features. Design adaptations include sample size re-estimation, enrichment of patient population, dropping a treatment arm, etc. In this presentation I shall give an introduction of this topic and a brief overview of critiques and comments to such adaptation in the literature.
Wednesday April 9, 2008 at 4:00 PM in SEO 636