Statistics and Data Science Seminar
Wenting, Wu
UIC, Statistics
An Unified Approach for Measuring Agreement
Abstract: Assessing agreement plays an important role in assessing the
acceptability of a new or generic process, methodology, and formulation in
areas of laboratory performance, instrument or assay validation, method
comparisons, and individual bioequivalence. An introduction of current
existing methods for measuring agreement will be given. After that, an unified
approach for measuring agreement of k readers each with multiple readings will
be introduced. When each reader has only one reading, this mehtod degenerates
into the conventional overall agreement index. When there are only two
readers, it degenerates into the conventional concordance correlation
coefficient (CCC). When data are ordinal, it degenerates into the weighted
kappa coefficient. When data are binary, it degenerates into the kappa
coefficient. The approach uses generalized estimation equations (GEE) to
model various functions of variance components. Some simulation results will
be presented and followed by an example.
Drinks,...
Wednesday October 26, 2005 at 3:30 PM in SEO 512